Medical Toxicology and Applied Pharmacology

Drug Overdose and Poisoning Management

Management of drug overdoses and poisonings has progressed through improved diagnostic protocols, antidote availability, and supportive care strategies. New treatment guidelines emphasize early identification of toxic agents, such as opioids and benzodiazepines, along with timely intervention. The integration of toxicology databases, telemedicine, and artificial intelligence enhances clinicians' ability to respond quickly to overdose cases. Tailored detoxification, gastric decontamination, and organ support remain critical to minimizing mortality and long-term damage.