Medical Toxicology and Applied Pharmacology

Adverse Drug Reactions and Drug Safety

Monitoring adverse drug reactions (ADRs) is essential for ensuring drug safety. ADRs, ranging from mild effects to severe toxicity, can result from drug interactions, genetic factors, or dosage errors. Pharmacovigilance systems have evolved to track ADRs post-marketing, enabling early detection of risks. Personalized medicine, through pharmacogenomics, improves drug safety by predicting individual responses to therapies, minimizing ADRs, and optimizing treatment. Regulatory frameworks also play a crucial role in maintaining drug safety.